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ORIGINAL ARTICLE
Year : 2017  |  Volume : 31  |  Issue : 3  |  Page : 190-194

Study to correlate clinical and histopathological characteristics of pterygium in predicting its recurrence


1 Department of Ophthalmology, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Pune, Maharashtra, India
2 Department of Pathology, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Pune, Maharashtra, India

Correspondence Address:
Banyameen Mohamad Iqbal
Department of Pathology, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Pimpri, Pune - 411 018, Maharashtra
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jms.jms_104_16

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Background: Pterygium is a fleshy, triangular, or wing-shaped growth of the conjunctiva that encroaches onto the cornea. It is an active, invasive, inflammatory process associated with cellular proliferation, connective tissue remodeling, and angiogenesis. Materials and Methods: It is a prospective 2-year study. One hundred eyes with pterygium presenting in ophthalmology department in a tertiary care hospital in Western Maharashtra, India, were selected. Clinical and histopathological characteristics of pterygia were noted. Statistical analysis of the obtained results was carried out by a statistical program package (SPSS, version 15 and Epi Info, version 7). Results: Out of 100 pterygia, 93% were nasally located, 17% were seen in bilateral eyes, 91% of the pterygia were ≤4 mm in size, and 75% were progressive in nature. Stocker's line was seen in 25% of cases whereas Fuchs spots were seen in only 4% of cases. Thirty-four percent of pterygia were having Grade 1 inflammation whereas 18% were having Grade 0 and Grade IV inflammation each. Similarly 36% pterygia were showing grade II vascularization and 35% were showing grade III fibrinoid necrosis. A total number of pterygia that recurred in our study (n = 3) were showing high grades of inflammation, vascularization, and fibrinoid change (Grade IV each). Conclusion: All the pterygia were surgically removed with conjunctival autograft technique, and the pterygia which recurred in our study (n = 3) were all nasally located, progressive in nature, and > 4 mm in size with positive Fuchs spots and negative Stocker's line. All were showing high-grade (Grade IV) inflammation, vascularization, and fibrinoid change.


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