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CASE REPORT
Year : 2019  |  Volume : 33  |  Issue : 2  |  Page : 101-103

Pemphigus vegetans: A rare variant of pemphigus vulgaris


1 Department of Pathology, Dr. D.Y. Patil Medical College, Hospital and Research Centre, Pune, Maharashtra, India
2 Department of Dermatology, Dr. D.Y. Patil Medical College, Hospital and Research Centre, Pune, Maharashtra, India

Correspondence Address:
Banyameen Iqbal
Department of Pathology, Dr. D.Y. Patil Medical College, Hospital and Research Centre, Pimpri, Pune - 411 018, Maharashtra
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jms.jms_20_19

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Pemphigus vegetans (PV) is a rare clinical variant of pemphigus vulgaris and comprises up to 1%–2% of all pemphigus cases. It is characterized by vegetative plaques in the inguinal folds, flexural areas, oral mucosa, trunk, and thighs. It is accompanied by the presence of autoantibodies against desmoglein-3. We are presenting a case of a 36-year-old man with oral ulcers and multiple pustules in the flexural areas, inguinal region, and thighs. Systemic examination was uneventful. Skin biopsy was taken from the lesion over the thigh and subjected to light microscopy and immunofluorescence examinations. Based on clinical findings, histopathological characteristics, and direct immunofluorescence, a final diagnosis of PV was made.


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