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Year : 2016  |  Volume : 30  |  Issue : 2  |  Page : 116-120

Prophylactic intravenous ephedrine for prevention of hypotension in cesarean section during spinal anesthesia: A comparative study

1 Department of Anaesthesiology, RIMS, Imphal, Manipur, India
2 Department of Anaesthesiology, JNIMS, Imphal, Manipur, India

Correspondence Address:
Takhelmayum Hemjit Singh
Department of Anaesthesiology, Regional Institute of Medical Sciences, Imphal - 795 004, Manipur
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0972-4958.182922

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Background: Spinal anesthesia is the most common preferred technique for cesarean delivery. However, it is associated with hypotension which is detrimental to both the mother and fetus. The study has been undertaken to determine the effect of bolus intravenous ephedrine in ameliorating spinal-induced hypotension. Materials and Methods: Fifty primiparous parturients scheduled for cesarean section were randomly allocated into two groups of 25 patients each: Group 1 (study) and Group 2 (control) to receive either 1 ml of 5 mg bolus intravenous ephedrine or equal volume of normal saline, respectively, just after 10 mg of 0.5% intrathecal bupivacaine. Results: Significant fall in systolic blood pressure from its baseline value occurs at all time intervals in both the groups, except up to the 4 th min in the ephedrine group. The incidences of hypotension between the two groups were 60% and 72% in the ephedrine and control group, respectively (P > 0.05). Conclusion: Prophylactic use of intravenous ephedrine did not significantly decrease the incidence of maternal hypotension.

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