Print this page Email this page
Users Online: 439
Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Contacts Login 
CASE REPORT
Year : 2016  |  Volume : 30  |  Issue : 3  |  Page : 179-181

Isolated extrapontine myelinolysis due to hemodialysis in a normonatremic individual


1 Department of Radiology, Narayana Medical College and Hospital, Nellore, Andhra Pradesh, India
2 Department of Neurosurgery, Narayana Medical College and Hospital, Nellore, Andhra Pradesh, India

Correspondence Address:
Amit Agrawal
Department of Neurosurgery, Narayana Medical College and Hospital, Chinthareddypalem, Nellore - 524 003, Andhra Pradesh
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0972-4958.191186

Rights and Permissions

Osmotic demyelination syndrome primarily occurs due to an imbalance of serum electrolytes and caused by rapid correction of hyponatremia. Isolated extrapontine myelinolysis is extremely rare, etiopathogenesis of which may be related to osmotic stress resulting from electrolyte disequilibrium. Extrapontine sites involved in osmotic demyelination syndrome show abundant oligodendrocytes, which are highly susceptible to osmotic stresses. Myelin vacuolization followed by intramyelinic splitting and disruption of myelin sheaths occur due to rapid osmolar fluctuations. Symmetrical hyperintensities showing restriction, which resolve in subsequent magnetic resonance scans can help in clinching the diagnosis of this condition in a given clinical setting.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed1950    
    Printed16    
    Emailed0    
    PDF Downloaded110    
    Comments [Add]    

Recommend this journal