Journal of Medical Society

ORIGINAL ARTICLE
Year
: 2017  |  Volume : 31  |  Issue : 2  |  Page : 123--126

Efficacy of intravenous acetaminophen and lidocaine on propofol injection pain


Feiga Luckson Gangmei, Longjam Eshori, Sanasam Sarat Singh, Nongthombam Ratan Singh, Mohan Thapa, Sagar Debbarman 
 Department of Anaesthesiology, Regional Institute of Medical Sciences, Imphal, Manipur, India

Correspondence Address:
Longjam Eshori
Department of Anaesthesiology, Regional Institute of Medical Sciences, Imphal, Manipur
India

Background: Propofol injection pain is one of the significant drawbacks to its use as an intravenous (IV) anesthetic induction agent so this study has been undertaken to compare the efficacy of IV acetaminophen and lidocaine on propofol injection pain. Materials and Methods: After obtaining Institutional Ethical Committee approval, ninety adult patients of ages 18–60 years of both sexes and American Society of Anaesthesiologist I and II who underwent elective surgery from September 2013 to September 2015 in the Tertiary Care Hospital, Imphal, were randomly allocated to one of the three groups to receive 10 ml saline (Group 1), 40 mg lidocaine (loxicard) in 10 ml saline (Group 2) and acetaminophen 100 mg (10 ml) (Group 3) to compare the pain efficacy during propofol injection into the large dorsal vein on the left hand. Pain was assessed with a verbal rating scale. Results: It was observed that the number of patients experiencing pain was 20 (66.67%), i.e., mild: moderate: severe - 11 (36.67%): 6 (20%): 3 (10%) in Group 1, in Group 2 the incidence was 2 (6.67%) i.e., mild: moderate: severe - 2 (6.67%): 0: 0, and in Group 3 it was 6 (20%) i.e., mild: moderate: severe - 5 (16.67%): 1 (3.33%): 0, respectively (P < 0.001). Conclusion: IV acetaminophen and lidocaine could significantly reduce pain during propofol injection with a significant P< 0.001.


How to cite this article:
Gangmei FL, Eshori L, Singh SS, Singh NR, Thapa M, Debbarman S. Efficacy of intravenous acetaminophen and lidocaine on propofol injection pain.J Med Soc 2017;31:123-126


How to cite this URL:
Gangmei FL, Eshori L, Singh SS, Singh NR, Thapa M, Debbarman S. Efficacy of intravenous acetaminophen and lidocaine on propofol injection pain. J Med Soc [serial online] 2017 [cited 2021 Sep 24 ];31:123-126
Available from: https://www.jmedsoc.org/article.asp?issn=0972-4958;year=2017;volume=31;issue=2;spage=123;epage=126;aulast=Gangmei;type=0